| Functional Microspheres |
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© 2009 XL Sci-Tech, Inc. All Rights Reserved
Bioactive Glass has been known for its excellent bioactivity (or
biocompatibility) and a range of successful applications replacing
tissues from middle-ear to dental defects. Bioglass(R) is based on
the well studied and published original "grand father" composition
45S5 . A recent lecture by Dr. Larry Hench provided a 40-year
retrospective of the Bioglass(R) evolution with an imnortant shift
from tissue replacement to emphasis on stimulating tissue
re-generation (osteogenesis) using bioactive glasses.
biocompatibility) and a range of successful applications replacing
tissues from middle-ear to dental defects. Bioglass(R) is based on
the well studied and published original "grand father" composition
45S5 . A recent lecture by Dr. Larry Hench provided a 40-year
retrospective of the Bioglass(R) evolution with an imnortant shift
from tissue replacement to emphasis on stimulating tissue
re-generation (osteogenesis) using bioactive glasses.
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Bioactive Glass Microspheres: 4PiGraft(TM)
Bioactive Glass Microspheres offer important
advantages over traditional fritted glass powders:
advantages over traditional fritted glass powders:
- Consistent and controlled surface to mass
ratio for controlled release of Ca and Si. - Best flow possible for fast and trouble-free
delivery - Optimal gap among bioactive glass
microspheres for tissue in-growth
| Shape and Surface of Typical Bioactive Microspheres (~250um showing in SEM photo). Production capacity ranges from sub-micron to mm with narrow bioactive glass microspheres size distribution. |
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While there are a variation of the original "grand father" 45S5
composition, nearly all FDA approved products uses the original 45S5
composition which contains 45% silicon oxide and 6% phosphorus
oxide by weight, respectively. XL Sci-Tech has developed a
proprietary technology for volume production of 45S5 bioactive glass
microspheres. XL Sci-Tech is also capable of processing customer
supplied fritted bioactive glass powders into high quality bioactive
glass microspheres without changing surface chemistry or any
decrease in bioactivity. Contact us.
composition, nearly all FDA approved products uses the original 45S5
composition which contains 45% silicon oxide and 6% phosphorus
oxide by weight, respectively. XL Sci-Tech has developed a
proprietary technology for volume production of 45S5 bioactive glass
microspheres. XL Sci-Tech is also capable of processing customer
supplied fritted bioactive glass powders into high quality bioactive
glass microspheres without changing surface chemistry or any
decrease in bioactivity. Contact us.